Disorder of sex development

Disorders of sex development, or DSD previously called intersex , includes a range of conditions that lead to abnormal development of the sex organs and atypical genitalia — genitalia that is not clearly male or female. Often, the cause of DSD is unknown. The development of sex organs is a very complex process comprised of many steps, and errors in any of these steps can result in DSD. Abnormalities in the chromosomes, or in the production and activity of hormones, may also play a role. The most common cause of atypical genitalia is an abnormality in the hormone-producing adrenal glands, which can cause females to develop male characteristics.
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Explaining Disorders of Sex Development & Intersexuality

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Disorders of sex development - Wikipedia

Normal sex development depends on the precise spatio-temporal sequence and coordination of mutually antagonistic activating and repressing factors. These factors regulate the commitment of the unipotential gonad into the binary pathways governing normal sex development. Typically, the presence of the SRY gene on the Y chromosome triggers the cascade of molecular events leading to male sex development. Disorders of sex development comprise a heterogenous group of congenital conditions associated with atypical development of internal and external genitalia.
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Your Child

Disorders of sex development DSDs , also known as differences in sex development , diverse sex development and variations in sex characteristics VSC , [2] are medical conditions involving the reproductive system. More specifically, these terms refer to " congenital conditions in which development of chromosomal , gonadal, or anatomical sex is atypical. The term has been controversial, and research has shown that affected people experience a negative impact, with the terminology impacting choice and utilization of health care providers. DSDs are medical conditions involving the way the reproductive system develops from infancy and before birth through young adulthood. There are several types of DSDs and their effect on the external and internal reproductive organs varies greatly.
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These are children born with a disorder of sex development DSD — a group of about 60 conditions in which biological sex, or being male or female, is not clear. Before birth, in the first weeks of pregnancy , females and males look nearly identical. Then, because of a complicated interaction between genes and chemicals called hormones, the differences we have come to expect slowly take shape. A DSD is a mismatch between a child's chromosomes, or genetic material, and the appearance of the child's genitals. A child may present with a DSD in infancy, childhood or adolescence.
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